diff --git a/gcc/ChangeLog b/gcc/ChangeLog
index ff8fc9a21b9f..44883d0b303a 100644
--- a/gcc/ChangeLog
+++ b/gcc/ChangeLog
@@ -1,3 +1,10 @@
+2010-11-26  Richard Guenther  <rguenther@suse.de>
+
+	PR tree-optimization/46528
+	PR debug/46338
+	* profile.c (branch_prob): Do not split blocks based on locations
+	from debug statements.
+
 2010-11-26  Jakub Jelinek  <jakub@redhat.com>
 
 	PR middle-end/46647
diff --git a/gcc/profile.c b/gcc/profile.c
index ffcd802375ff..b8a43de3463e 100644
--- a/gcc/profile.c
+++ b/gcc/profile.c
@@ -940,7 +940,8 @@ branch_prob (void)
 	  for (gsi = gsi_last_bb (bb); !gsi_end_p (gsi); gsi_prev (&gsi))
 	    {
 	      last = gsi_stmt (gsi);
-	      if (gimple_has_location (last))
+	      if (!is_gimple_debug (last)
+		  && gimple_has_location (last))
 		break;
 	    }